CovidPublicV1, Main, Exploration, bibRecord, 000115

Model Calculations of Aerosol Transmission and Infection Risk of COVID-19 in Indoor Environments.

Identifieur interne : 000115 ( Main/Exploration ); précédent : 000114; suivant : 000116

Model Calculations of Aerosol Transmission and Infection Risk of COVID-19 in Indoor Environments.

Auteurs : Jos Lelieveld [Allemagne, Chypre (pays)] ; Frank Helleis [Allemagne] ; Stephan Borrmann [Allemagne] ; Yafang Cheng [Allemagne] ; Frank Drewnick [Allemagne] ; Gerald Haug [Allemagne] ; Thomas Klimach [Allemagne] ; Jean Sciare [Allemagne, Chypre (pays)] ; Hang Su [Allemagne] ; Ulrich Pöschl [Allemagne]

Source :

International journal of environmental research and public health [ 1660-4601 ] ; 2020.

RBID : pubmed:33153155

Descripteurs français

KwdFr :
- Algorithmes (MeSH), Aérosols (MeSH), Betacoronavirus (MeSH), Filtration (MeSH), Humains (MeSH), Infections à coronavirus (prévention et contrôle), Infections à coronavirus (transmission), Masques (MeSH), Microbiologie de l'air (MeSH), Modèles théoriques (MeSH), Pandémies (prévention et contrôle), Pneumopathie virale (prévention et contrôle), Pneumopathie virale (transmission), Ventilation (MeSH).
MESH :
- prévention et contrôle : Infections à coronavirus, Pandémies, Pneumopathie virale.
- Algorithmes, Aérosols, Betacoronavirus, Filtration, Humains, Infections à coronavirus, Masques, Microbiologie de l'air, Modèles théoriques, Pneumopathie virale, Ventilation.

English descriptors

KwdEn :
- Aerosols (MeSH), Air Microbiology (MeSH), Algorithms (MeSH), Betacoronavirus (MeSH), COVID-19 (MeSH), Coronavirus Infections (prevention & control), Coronavirus Infections (transmission), Filtration (MeSH), Humans (MeSH), Masks (MeSH), Models, Theoretical (MeSH), Pandemics (prevention & control), Pneumonia, Viral (prevention & control), Pneumonia, Viral (transmission), SARS-CoV-2 (MeSH), Ventilation (MeSH).
MESH :
- chemical : Aerosols.
- prevention & control : Coronavirus Infections, Pandemics, Pneumonia, Viral.
- transmission : Coronavirus Infections, Pneumonia, Viral.
- Air Microbiology, Algorithms, Betacoronavirus, COVID-19, Filtration, Humans, Masks, Models, Theoretical, SARS-CoV-2, Ventilation.

Abstract

The role of aerosolized SARS-CoV-2 viruses in airborne transmission of COVID-19 has been debated. The aerosols are transmitted through breathing and vocalization by infectious subjects. Some authors state that this represents the dominant route of spreading, while others dismiss the option. Here we present an adjustable algorithm to estimate the infection risk for different indoor environments, constrained by published data of human aerosol emissions, SARS-CoV-2 viral loads, infective dose and other parameters. We evaluate typical indoor settings such as an office, a classroom, choir practice, and a reception/party. Our results suggest that aerosols from highly infective subjects can effectively transmit COVID-19 in indoor environments. This "highly infective" category represents approximately 20% of the patients who tested positive for SARS-CoV-2. We find that "super infective" subjects, representing the top 5-10% of subjects with a positive test, plus an unknown fraction of less-but still highly infective, high aerosol-emitting subjects-may cause COVID-19 clusters (>10 infections). In general, active room ventilation and the ubiquitous wearing of face masks (i.e., by all subjects) may reduce the individual infection risk by a factor of five to ten, similar to high-volume, high-efficiency particulate air (HEPA) filtering. A particularly effective mitigation measure is the use of high-quality masks, which can drastically reduce the indoor infection risk through aerosols.

DOI: 10.3390/ijerph17218114
PubMed: 33153155
PubMed Central: PMC7662582

Affiliations:

Links toward previous steps (curation, corpus...)

to stream Main, to step Corpus: 000050
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Le document en format XML

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<term>Coronavirus Infections (transmission)</term>
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<front><div type="abstract" xml:lang="en">The role of aerosolized SARS-CoV-2 viruses in airborne transmission of COVID-19 has been debated. The aerosols are transmitted through breathing and vocalization by infectious subjects. Some authors state that this represents the dominant route of spreading, while others dismiss the option. Here we present an adjustable algorithm to estimate the infection risk for different indoor environments, constrained by published data of human aerosol emissions, SARS-CoV-2 viral loads, infective dose and other parameters. We evaluate typical indoor settings such as an office, a classroom, choir practice, and a reception/party. Our results suggest that aerosols from highly infective subjects can effectively transmit COVID-19 in indoor environments. This "highly infective" category represents approximately 20% of the patients who tested positive for SARS-CoV-2. We find that "super infective" subjects, representing the top 5-10% of subjects with a positive test, plus an unknown fraction of less-but still highly infective, high aerosol-emitting subjects-may cause COVID-19 clusters (>10 infections). In general, active room ventilation and the ubiquitous wearing of face masks (i.e., by all subjects) may reduce the individual infection risk by a factor of five to ten, similar to high-volume, high-efficiency particulate air (HEPA) filtering. A particularly effective mitigation measure is the use of high-quality masks, which can drastically reduce the indoor infection risk through aerosols.</div>
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<Abstract><AbstractText>The role of aerosolized SARS-CoV-2 viruses in airborne transmission of COVID-19 has been debated. The aerosols are transmitted through breathing and vocalization by infectious subjects. Some authors state that this represents the dominant route of spreading, while others dismiss the option. Here we present an adjustable algorithm to estimate the infection risk for different indoor environments, constrained by published data of human aerosol emissions, SARS-CoV-2 viral loads, infective dose and other parameters. We evaluate typical indoor settings such as an office, a classroom, choir practice, and a reception/party. Our results suggest that aerosols from highly infective subjects can effectively transmit COVID-19 in indoor environments. This "highly infective" category represents approximately 20% of the patients who tested positive for SARS-CoV-2. We find that "super infective" subjects, representing the top 5-10% of subjects with a positive test, plus an unknown fraction of less-but still highly infective, high aerosol-emitting subjects-may cause COVID-19 clusters (>10 infections). In general, active room ventilation and the ubiquitous wearing of face masks (i.e., by all subjects) may reduce the individual infection risk by a factor of five to ten, similar to high-volume, high-efficiency particulate air (HEPA) filtering. A particularly effective mitigation measure is the use of high-quality masks, which can drastically reduce the indoor infection risk through aerosols.</AbstractText>
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Model Calculations of Aerosol Transmission and Infection Risk of COVID-19 in Indoor Environments.

Model Calculations of Aerosol Transmission and Infection Risk of COVID-19 in Indoor Environments.

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